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Célia Souque

Célia Souque​

DPhil Student - Interdisciplinary Bioscience DTP

Email: celia.souque@worc.ox.ac.uk

What's my research about?

If we want to fight successfully the threat posed by the rise of antimicrobial resistant bacteria we need not only to develop new antibiotics but also to try to understand the mechanisms used by bacteria to spread and share resistance genes. 

My main object of study is the integron, a bacterial ‘genetic shuffling device’ heavily involved in the spread of multidrug resistance in hospital, and quantifying its evolutionary benefits. I am also interested in discovering how transformation, the mechanism by which bacteria take in and incorporate foreign DNA into their own genome, came to evolve, despite its initial cost to its user. 

I aim answer these questions with both experimental and theoretical approaches, using experimental evolution and modeling. 

I am co-supervised by Craig MacLean (https://macleanlab.wordpress.com).